GCM1


Chorion-specific transcription factor GCMa is a protein that, in humans, is encoded by the GCM1 gene.
This gene encodes a DNA-binding protein with a gcm-motif. The encoded protein is a homolog of the Drosophila glial cells missing gene. This protein binds to the GCM-motif CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.