Fly spray


Fly spray is a chemical insecticide that comes in an aerosol can that is sprayed into the air to kill flies. Fly sprays will kill various insects such as house flies and wasps.

Principles

Fly spray contains chemicals that bind to and permanently block the action of an enzyme called acetylcholinesterase. Acetyl choline is the nerve transmitter substance released by motor neurones to stimulate muscle contraction. The muscles relax when the ACh is removed from the neuromuscular junction by the action of acetylcholinesterase.
By inhibiting the cholinesterase the insect can no longer break down ACh in the NMJ and so its muscles lock up in a state of tetany making flying and respiration impossible, and the insect then dies of asphyxiation.

Safety

Fly spray is dangerous to pets as well as fish and should be used with caution.
In the United States, fly sprays often contain the powerful insect toxin dichlorvos which is often targeted by environmental groups as a carcinogenic compound.