Fluvalinate


Fluvalinate is a synthetic pyrethroid chemical compound contained as an active agent in the products Apistan, Klartan, and Minadox, that is an acaricide, commonly used to control Varroa mites in honey bee colonies, infestations that constitute a significant disease of such insects.
Fluvalinate is a stable, nonvolatile, viscous, heavy oil soluble in organic solvents.
Although the compound may be found in drones, a study has found honey samples virtually absent of fluvalinate, on account of its affinity to beeswax.

Stereoisomerism

Fluvalinate is synthesized from racemic valine , the synthesis is not diastereoselective. Thus, fluvalinate is a mixture of four stereoisomers, each about 25%.
Fluvalinate stereoisomers

-configuration

-configuration

-configuration

-configuration

Tau-fluvalinate is the trivial name for -fluvalinate. The C atom in the valinate structure is in -absolute configuration, while the second chiral atom is a mixture of - and -configurations:
τ-Fluvalinate diastereomers

-configuration

-configuration