Kazadi was born in Katende wa Bakwa Mwanza, in the Kasai-Occidental region on April 24, 1925. His parents, Helene Ngalula Mulanga and Jean Dibomba Kabongo, had four children, of which Kazadi was the only son. Higher education was mainly provided by Catholic and Protestant missionaries. Kazadi had successfully completed high school at the Scheutiste Mission of Kabwe from 1934 to 1939. He distinguished himself through his abilities and the conspicuous influence of a Catechist father, so he was sent to the Small Seminary of Kabwe Ste Therese in December 1939, as few other choices were available to the elite. After six years of higher education, in 1946 he was admitted to the Large Seminary of Kabwe, in order to pursue studies in philosophy and theology for the next eight years. Kazadi was on the path to enter priesthood after 14 years of seminary studies, but he abandoned to protect his clan's lineage. Therefore, in 1952, he undertook career in public service. Kazadi first became the Official to the Provincial Secretariat, and later became a Specialist at the Governor Cabinet of the Kasai Province. In parallel with his administrative career, Kazadi participated in the independence struggle. Using the pen name "Kazadi wa Kabwe", he distinguished himself through his writings. In 1954, the first Congolese university, Lovanium University, opened in Leopoldville. His ambition to acquire a better education despite his familial duties, led him to enroll in 1955 in the Political and Social Sciences Department. He received a degree in sociology in 1960. He wrote a memoir upon completing his studies, entitled The Life of An Unemployed in Kinshasa in 1960. During his years at Lovanium, he was nicknamed "Bismarck" due to his loyalty and firmness, based on German chancellorOtto von Bismarck. Kazadi was fluent in Chinese, Dutch, French, English, Latin, Swahili, Kikongo, Lingala, and Ciluba. He read extensively and loved classical music, which he was also able to read. He was a proficient harmonium player. He married Madeleine Mianda Ngadu in 1953.
Political career
General Commissioner of Defense
On 14 September 1960, colonel Mobutu took over for the first time, neutralizing President Kasa-Vubu, arresting Prime Minister Lumumba and seizing power. Mobutu called upon the people's elite, the few university graduates still residing in the country, to form a government: the College of Commissioners-General. These individuals were in charge until February 1961. Kazadi was one of these individuals and was placed as General Commissioner of National Defense.
The Lulua–Baluba conflicts were stimulated by the colonizers and Lumumba's refusal of a resolution on behalf of the MNC. The exodus of the Balubas ensued, led them to relocate to southern Kasai. Kasai seceded as did Katanga. The Independent State of Southern Kasai existed from August 1960 to July 1961. Kazadi was its Police Force Minister. At the end of the Independent State of Southern Kasai, he escaped to Brazzaville.
Under Mobutu
Two years after the resumption of power by Mobutu in 1964, elections took place and Kazadi was elected National Deputy in 1966. Following this, he became Head of Research at the Office of National Research and Development. The creation of the Popular Movement of the Revolution in 1967, a party led by President Mobutu, effectively provoked the closing and dismissal of Parliament. In 1969, he was named Commissioner of State for Public Matters and Territorial Management. In the course of his passage, he founded the School of Truck-Driving Engineers in Kingabwa, Kinshasa. In 1970, he was promoted to Commander of National Order of the Leopard and was later appointed as Minister of State. Kazadi retired from political affairs in 1980.