FUT7
Alpha--fucosyltransferase is an enzyme that in humans is encoded by the FUT7 gene.Function
The sialyl Lewis x oligosaccharide determinant is an essential component of leukocyte counterreceptors for E-selectin- and P-selectin- mediated adhesions of leukocytes. This oligosaccharide molecule is displayed on the surfaces of granulocytes, monocytes, and natural killer cells. Formation of leukocyte adhesions to these selectins is an early and important step in the process that ultimately allows leukocytes to leave the vascular tree and become recruited into lymphoid tissues and sites of inflammation.
