FOXA3


Hepatocyte nuclear factor 3-gamma, also known as forkhead box protein A3 or transcription factor 3G is a protein that in humans is encoded by the FOXA3 gene.

Function

HNF-3G is a member of the forkheadclass of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.