Anderson grew up in Tulsa, Oklahoma, the daughter of a sculptor. She attended Nathan Hale High School and the University of Tulsa, graduating with a major in telecommunications and a minor in theater. While in school, she worked as a disc jockey at Tulsa's only jazz radio station and also began working in television, eventually hosting her own arts program. After college, she moved to Los Angeles to pursue a career in radio and television. She signed with a modeling agency and worked steadily in New York City, Paris, Milan, and Los Angeles. She appeared in fashion layouts in magazines such as Vogue and Interview. While in Italy, she played the lead in a short experimental film about an Italian vision of the United States called Through Your Eyes. Her first role in a full-length movie was in the 1988 movieLifted, and her breakthrough role came in 1989 in the horror movie' as Greta Gibson. Anderson appeared in three TV episodes of "Twin Peaks", playing twin sisters, Emerald and Jade in Invitation to Love. She starred in the 1991 erotic suspense thrillerZandalee with Nicolas Cage, Judge Reinhold, and Joe Pantoliano. In 1991, she starred in a suspense thriller Shadows of the Past, as Jackie Delaney with Nicholas Campbell. In 1995, she starred with Scott Valentine in Object of Obsession as Margaret, a woman taken hostage by her mysterious new lover. Her last movie was in 2000 in the film Ascension. Anderson has made many guest appearances on TV shows from Silk Stalkings, Dream On, Twin Peaks, to Red Shoe Diaries. The 5-foot 11-inch brunette modeled for various fashion magazines, as well as for photographers Helmut Newton, Douglas Sutter, and sculptor Robert Graham. She has appeared on the cover of at-least five magazines. In 2010 Anderson appeared in '. Anderson was also featured in articles in such magazines as the May 1991 Premiere Magazine, by Phoebe Hoban, the January 1991 Elle, as well as ITC Entertainment's press kit for the 1991 movieZandalee.
Anderson is shown on the cover of the EP "Embarrassing Love Songs Two: Greta Gibson Forever" by singer/songwriter Nicole Dollanganger. This is a reference to her role in .