Wicks enrolled at West Virginia University in 2003. Wicks played backup spur safety in 2004 as a redshirt freshman. Wicks recorded 14 tackles for the season and a 34-yard interception returned for a touchdown against Virginia Tech. Wicks also earned three tackles in the win against Temple University. As a redshirt sophomore in 2005, Wicks played backup to all-conference safeties Mike Lorello and Jahmile Addae. Even though playing backup, Wicks earned second-team all-Big East honors. Wicks totaled 61 tackles for the year and scored West Virginia's first score of the year: a 31-yard interception return against Syracuse University, also totaled four tackles and a sack against the Orange. Wicks forced a Woffordfumble and an eight-yard sack. Wicks forced a Maryland fumble, seven tackles against East Carolina University, eight tackles against Virginia Tech, and nine tackles against Louisville. Wicks also won the game for West Virginia against Louisville, by tackling Louisville quarterbackBrian Brohm on the two-point conversion in the 3rd overtime. Wicks was the leading tackler against Cincinnati and forced a fumble. Wicks ended the regular season with a key 4th quarter interception against the South Florida Bulls. Wicks recorded three tackles and recovered a fumble against the Georgia Bulldogs in the Sugar Bowl win. Wicks earned the Coaches Contribution Award, Defensive MVP against Syracuse and Cincinnati, and Big Easthonor roll against Syracuse. At the beginning of the 2006 season, Eric Wicks and fellow-Mountaineer Kevin "Boo" McLee made the Bronko Nagurski Trophy watch list. Although neither Wicks nor McLee won the award, both had stellar years. Wicks totaled 67 tackles and a team second-best three interceptions, to Quinton Andrews' four. Wicks' interceptions came to Eastern Washington, Mississippi State, and USF. Eric Wicks' interception against Mississippi State came in the endzone to save a touchdown. Against ECU, Wicks led the team with eight tackles, then eight tackles against Syracuse. In the Gator Bowl against Georgia Tech, Wicks recorded 5 tackles. Wicks was also named to the first-team all-Big East squad at the end of the season. In the preseason of 2007, Wicks was selected as the #7 safety in the nation by Lindy's, was a second-team All-American selection, and was a preseason first-team all-Big East selection. He was also selected on the Jim Thorpe Award watchlist and Lott Trophy watchlist for defensive backs and defensive players, respectively. Against Marshall in the in-state rivalry game, Wicks recorded eight tackles as the Mountaineers won 48-23. In the third game of the season against Maryland, Wicks has two interceptions in the first half of the ballgame. Against ECU in the next game, Wicks recorded six tackles and a sack in the 48-7 win. In the 21-13 loss to USF, Wicks had five tackles, a pass deflection, and a fumble recovery. Against Mississippi State, Wicks had four tackles and a sack. In the Mountaineers' dramatic 38-31 win over Louisville, Wicks had possibly the greatest game of his career. He had a fumble recovery after John Holmes hit quarterback Brian Brohm, knocking the ball loose, that he took 44 yards for a touchdown. Then in the fourth quarter, Wicks had a diving interception that was key in the final six minutes of the game. Wicks' performance in the Louisville win earned his Big East Defensive Player of the Week honors. In the 66-21 victory over #20 Connecticut to clinch the Big East title, Wicks recorded 4 tackles and two pass deflections. At the end of the regular season, Wicks earned the team's Coaches Contribution Award. In Wick's final collegiate game, the 48-28 victory over Oklahoma in the Fiesta Bowl, Wicks had two tackles and two pass deflections. Wicks totaled 45 tackles on the season and three interceptions, and also a fumble return for a touchdown. Eric Wicks finished his collegiate career with 187 career tackles, 9 interceptions and 3 Touchdowns.
Professional career
Pre-draft
After the 2007 season, Wicks graduated and entered the 2008 NFL Draft. He was not invited to the NFL Scouting Combine, though he did work out at the West Virginia's Pro Day on March 13, 2008. Wicks went undrafted in the NFL Draft, becoming an undrafted free agent.
Seattle Seahawks
Wicks was signed by the Seattle Seahawks after being undrafted in the 2008 NFL Draft. He was placed on injured reserve on August 14 and was released by the team with an injury settlement four days later.
