The Knowsley Estate has residential properties in the rural parishes of Knowsley, Eccleston, Rainford, Bickerstaffe and Ormskirk. It also offers commercial properties as part of the Stanley Grange Business Village, converted from a range of Victorian farm buildings on the estate and opened in June 2013. The Grade II* listed Knowsley Hall and surrounding 2,500 acres of parkland have also been used as locations for several television programmes and films including Apparitions, The Liver Birds as well as television soap operas, Hollyoaks and Coronation Street. In 2008, the house received a five-star gold rating for accommodation from inspectors at VisitEngland, the only stately home to be so rated. In 2010, Lord Derby announced his ‘Green’ policies for the estate, which included conservation and generation of efficient energy usage.
Stanley's maternal grandmother, Catherine, was a well known racehorse trainer in Wiltshire notably College House, Lambourn, from where she sent out The Schweppes Gold Trophy winner Ra Nova, among others. The Epsom Derby was named after the 12th Earl of Derby while The Oaks was named after the 12th Earl's house near Epsom. The Derby family can trace its horse racing heritage back to the 5th Earl of Derby in the sixteenth century. Stanley usually has one or sometimes two horses in training each year from Hatchfield stud farm, managed by his brother, Peter Stanley. Home to a small number of broodmares, Lord Derby's policy is to sell his colts and race the fillies. The Earl currently owns Ouija Board, winner of seven The Group/Grade 1 races, including The Oaks, Irish Oaks and Breeders' Cup Filly & Mare Turf in 2004, and the last-named race again in 2006. She also won the Prince of Wales's Stakes at Royal Ascot in June 2006. She was third in the Japan Cup following that last win, and was retired after going lame before her intended final start in the Hong Kong Vase at Sha Tin in December 2006. Ouija Board won over three million pounds in prize money. The Earl has published a book about her, Ouija Board: A Mare in a Million. Stanley's proposal to build 1,200 houses and a large industrial estate on historic studland at Hatchfield Farm in Newmarket, Suffolk, was met with opposition from local residents, businesses and the area's largest employers, including Tattersalls, the Jockey Club, Newmarket Racecourse, Newmarket's elected councillors, leading trainers and the local resident group Save Historic Newmarket.