Duilio Arigoni


Duilio Arigoni was a Swiss chemist and Emeritus Professor at ETH Zurich. He worked on the biosynthetic pathways of many organic natural substances.

Birth and education

Born in Lugano, Switzerland, Arigoni completed his undergraduate studies in Chemistry from ETH Zürich in 1951. He completed his Ph.D. in Chemistry from ETH Zurich in 1955. His doctoral thesis was “Über konfigurative Beziehungen Steroid- und Terpenverbindungen”.

Academic career

After completing his Ph.D., he became professor at ETH Zurich. He was also a visiting professor at Harvard University and Cambridge University. He has worked as a professor at ETH Zurich for over fifty years.

Research

Arigoni is known for his research in bio-organic stereochemistry. His major contributions are in the stereochemistry of enzyme-catalyzed reactions and in the biosynthesis of terpenes, alkaloids, and enzyme cofactors. He has explored the detailed stereochemical pathways by which enzymes convert their substrates into products. His strategy of penetrating into the structure of enzyme-substrate interactions by concentrating on the detailed stereochemical fate of isotopic substrate labels, led him to make basic contributions to the mechanism of enzymic reactions requiring coenzyme B12, one of the 'pigments of life'.

Awards

Arigoni has received numerous awards. In 1989 he was awarded the Wolf Prize in Chemistry along with Alan R. Battersby of the University of Cambridge "for their fundamental contributions to the elucidation of the mechanism of enzymic reactions and of the biosynthesis of natural products, in particular the pigments of life". He was elected a Foreign Honorary Member of the American Academy of Arts and Sciences in 1988.
Some other awards he has received are: