At the time of its release Ducati claimed that the 1199 Panigale was the world's most powerful production twin-cylinder engine motorcycle, with at 10,750 rpm, and torque at 9000 rpm on an engine test stand. With a claimed dry weight of and a curb weight of. Ducati said the 1199 had the highest power-to-weight and torque-to-weight ratios of production motorcycles. Motorcycle Consumer News tested the 2012 Panigale S at and torque at the rear wheel, with a wet weight. They measured a time of 2.98 seconds, a time of 9.91 seconds at, and a top speed to. Braking performance was in and average fuel economy was. Motorcycle Consumer News ranked the 2012 Panigale S with the best rear wheel horsepower to wet weight ratio, 1:2.47, of any bike the magazine had ever tested, as well as the 5th highest rear wheel horsepower, and the 10th highest top speed. The new Superquadro engine is exceptionally oversquare, with a bore:stroke ratio of 1.84:1. Whereas previous Ducatis had belt-driven overhead cams, this engine's valvetrain uses gears and chain. The engine serves as a stressed member, making the Panigale smaller and lighter than a conventionally framed motorcycle. The 1199 is also one of the first production sports motorcycles to feature electronically adjustable suspension. Rebound and compression damping is adjusted electronically while pre-load is still adjusted manually. The 1199's exhaust system and mufflers are underneath the engine, and not beneath the seat as on previous models, such as the 1198 and 1098.
Panigale R
In 2012, Ducati added the Panigale R World Superbikehomologation model for the 2013 model year. It has lightened engine internals, including titaniumconnecting rods, and carbon fiber external parts, raising power to and with the track only exhaust and reducing weight to. The top speed of the Panigale R was estimated by Road & Track to be with the track only Termignoni exhaust system it ships with, which they apparently derived from the speed at which the bike hits the rev limiter, assuming nominal gearing and wheel size.
Panigale S Senna
In 2013, Ducati again released a variant of their top of the range sportbike - this time the 1199 Panigale S Senna - dedicated to Formula 1 World Champion, Ayrton Senna. The predecessor was based on the 916 released in 1994; in both instances, net proceeds were donated to the Instituto Ayrton Senna charity.
1199 Superleggera
In 2014, Ducati launched the 1199 Superleggera. The philosophy behind this motorcycle was the largest reduction of weight possible, achieved through the use of exotic materials such as magnesium, carbon and titanium. This resulted in a dry weight of, and a wet weight of. Only 500 were produced.