Born in Treviso, Germinale started his career at Silea Calcio, located at Silea, the Province of Treviso. He then played for Treviso F.B.C. 1993 before joined Internazionale, which he supported at young age. He played the pre-season TIM Trophy in 2004 and a 6 more friendly appearances in 2005 Germinale finally made his official debut on 14 May 2006, the last match of the Serie A season, which he substituted Pierre Womé in the 58 minutes. The match ended in 2–2 draw with Cagliari. In summer 2006, he was loaned to Pizzighettone. After an unsuccessful half-season, he was loaned to Torres. In 2007–08 season, he was loaned to Serie C1 side Cittadella, re-joining Riccardo Meggiorini.
On 31 August 2009, Germinale transferred to Benevento of Prima Divisione Group A, signed a reported 3-year contract. Germinale seldom included in the starting XI, and on 31 January 2011 left for Como along with Walter Zullo. In the half season Germinale made 13 starts and 5 goals. On 31 August 2011 Germinale was sold to Serie B struggler AlbinoLeffe in temporary deal with option to purchase half of the registration rights, replacing the left of former Inter team-mate Matteo Momentè. Benevento also acquired Michael Cia in the same formula. Germinale took no.7 shirt previously owned by Cia. Germinale returned to Benevento for 2012–13 Lega Pro Prima Divisione season, which he scored 5 times. On 21 May 2013 he was released.
On 19 July 2013 he was signed by Catanzaro in 1+1 year contract. He scored 4 times in 2013–14 Lega Pro Prima Divisione. He also scored once against former club Benevento in promotion playoffs, losing 1–2.
On 31 August 2015 he was hired by Bassano Virtus; playing only a few games because of a knee injury. At the end of the season it is not confirmed, and accords with the Padova. On 31 January 2017 is made official his move, outright, to Fano.
Germinale never played for Italy youths team officially but received an Azzurri U18 call-up against Juniores League Best XI along with team-mate Matteo Momentè and Giacomo Bindi in 2006. The unofficial match Azzurrini won Juniores Best XI 3–1, the two Inter strikers scored 1 goal each.
