On 25 October 2015, Lukebakio made his professional debut in the 79th minute as a substitute for Youri Tielemans in a Belgian First Division A match against Club Brugge, which result in a 3–1 victory for Anderlecht. On 7 December 2015, Lukebakio signed a new five-year contract. Three days later, he made his first UEFA Europa League debut as a substitute for Imoh Ezekiel in the 66th minute of a 2–1 win against Qarabağ FK. On 29 January 2016, he played his first full match for Anderlecth, a 2–1 away win over Sint-Truden. On 28 February 2016, after coming on as a substitute for Alexander Büttner, he scored an equaliser in the 74th minute in a 3–3 draw against Standard Liège.
2016–17 season: Loan to Toulouse
On 31 August 2016, Lukebakio signed for French club Toulouse FC. On 8 January, he made his debut for Toulouse in the round of 64 of the Coupe de France, as a substitute, replacing Ola Toivonen in the 58th minute of a 2–1 home defeat against Olympique de Marseille. On 14 January, Lukebakio made his Ligue 1 debut as a substitute replacing Issiaga Sylla in the 56th minute of a 1–0 defeat against Nantes. Lukebakio ended his loan to Touluse with 5 apparences, all as a substitute.
On 2 July 2017, Lukebakio was signed by Charleroi on a season-long loan deal. On 29 July, he made his debut for Charleroi in a Belgian First Division A match against Kortrijk, which result in a 1–0 home win for Charleroi. On 5 August, he scored two goals in a match against Royal Excel Mouscron, the match finished with a 5–2 away victory for Charleroi. On 5 November, he scored his third goal in the 71st minute of a 3–1 away win over Antwerp.
On 30 January 2018, it was announced that Lukebakio would be joining Watford on a four-and-a-half-year deal. On 10 February, he made his Premier League debut during Watford's 2–0 defeat away to West Ham United.
On 23 July 2018, Lukebakio joined Fortuna Düsseldorf on a loan deal for the 2018–19 season. On 24 November 2018, Lukebakio became the first player in Bundesliga history to net three goals against Manuel Neuer in a 3–3 draw against Bayern Munich. The following month, he again found the back of the net in a 2–1 win, as Düsseldorf handed the Bundesliga leaders Borussia Dortmund their first league defeat of the season.
Hertha BSC
On 1 August 2019, Lukebakio transferred to Hertha BSC. He scored Hertha's first goal of the 2019–20 Bundesliga season in the team's opening match against Bayern Munich; a 2–2 draw.
International career
Lukebakio was born in Belgium to parents of Congolese descent. Lukebakio made his debut for the DR Congo national football team in a 1–0 loss to Kenya on 4 October 2016. He has since switched allegiance to represent the Belgium U21 side.
