Deltapapillomavirus


Deltapapillomavirus is a genus of viruses, in the family Papillomaviridae. Ruminants serve as natural hosts. There are currently seven species in this genus including the type species Deltapapillomavirus 1. Diseases associated with this genus include: warts of the skin and alimentary tract ; possibly responsible for the skin tumour equine sarcoid in horses and donkeys.

Taxonomy

Group: dsDNA

Structure

Viruses in Deltapapillomavirus are non-enveloped, with icosahedral geometries. The diameter is around 60 nm. Genomes are circular, around 8kb in length.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
DeltapapillomavirusIcosahedralT=7Non-envelopedCircularMonopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown.
Ruminants serve as the natural host. Transmission routes are contact.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
DeltapapillomavirusRuminantsEpithelial: mucous; epithelial: skinCell receptor endocytosisLysisNucleusNucleusContact