Born in Houston, Texas and raised in Spring, Texas, Murphy played high school baseball with fellow MLB players Chris George and Josh Barfield at Klein High School. At Klein, Murphy led the team to a state title in 1998 as a pitcher and outfielder, earned All-State honors, and was also a USA Today High School All-America Honorable Mention. As a senior, Murphy hit.500 with 12 home runs and 46 RBIs and was also a member of the National Honor Society. Murphy went on to Baylor University, turning down offers from the University of Texas, Rice University, and Texas A&M University. As a freshman, Murphy was the starting right fielder for the Bears, and hit.271 with five home runs. As a sophomore, Murphy hit.318 with six home runs, and hit.413 with 11 home runs in his junior and final season at Baylor. Murphy also played for the Wareham Gatemen of the Cape Cod Baseball League, where he was named co-MVP of the team.
Murphy made his MLB debut on September 2, 2006. He hit a 1–2 pitch into center field at Fenway Park in his first major leagueat-bat for his first major league hit on September 2, 2006. He hit his first MLB home run against New York Yankees pitcher, Jaret Wright, on September 17, 2006, at Yankee Stadium. In 2006, he appeared in 20 games for the Boston Red Sox batting.227 with a home run and 2 RBI. , triple-A affiliates of the Boston Red Sox, in
2007
Murphy began the 2007 season in the minor leagues. During his time in the major leagues with the Red Sox, he played 3 games with a triple in 2 plate appearances.
Texas Rangers (2007–2013)
2007
On July 31, 2007, Murphy was traded to the Texas Rangers in a package that sent relief pitcherÉric Gagné to Boston. For the rest of the 2007 season, Murphy played 43 games with the Rangers batting.340 with 2 home runs and 14 RBI. Overall in 2007 combined with two teams, Murphy played 46 total games batting.343 with 2 home runs and 14 RBI.
2008
On April 25, 2008, the Rangers beat the Minnesota Twins 6–5 on Murphy's walk-off RBI single in the bottom of the 10th. It was Murphy's first career walk-off hit. On August 1, 2008, Murphy capped a 3-run rally in the bottom of the 9th, hitting a walk-off 2-RBI single off B. J. Ryan as the Rangers beat the Toronto Blue Jays 9–8. In 2009 Murphy hit a walk-off single against Houston Astros closer, José Valverde. On August 7, 2008, Murphy was placed on the 15-day DL after suffering a knee injury in a collision at home plate with Iván Rodríguez of the New York Yankees. Murphy did not play another game in the 2008 season, when swelling to his knee cut his attempts at rehab short. For the 2008 season, Murphy played in 108 games batting.275 with 15 home runs and 74 RBI.
2009
In 2009, Murphy played in 128 games batting.269 with 17 home runs and 57 RBI.
2010
In 2010, Murphy played in 138 games batting.291 with 12 home runs and 65 RBI. His efforts led to the Rangers entering the World Seriesfor the first time in franchise history but the team would eventually lose the series to the San Francisco Giants.
2011
On opening day against the Boston Red Sox, Murphy hit a go-ahead, pinch-hit two-run double in the eighth inning that put the Rangers up, 7–5. Texas went on to win that game, 9–5. Two days later, in his first start of the season, he hit a home run against Clay Buchholz. During the 120 games Murphy played in during the 2011 season, he batted.275 and finished with 11 home runs and 46 RBI. In Game 7 of the 2011 World Series against the St. Louis Cardinals, Murphy was the final out of the series to fly out resulting in the Rangers losing their second straight World Series appearance.
2012
Murphy finished the 2012 season with a.304 batting average while slugging 15 home runs and 61 RBI in 147 games. His 4.0 WAR was the highest mark of his career.
2013
Murphy began the season as the starting left fielder. Jeff Baker was his backup throughout most of the season. In September, Craig Gentry and Jim Adduci took most of the starts in left with Gentry starting all of the final 10 games, while Murphy saw a lot of time pinch-hitting. In 142 games, Murphy hit.220/.282/.374 with 13 HR and 45 RBI in a down year from 2012. Murphy made his major league pitching debut on June 4, 2013 against the Boston Red Sox when he took the mound in the eighth inning of a 17-5 rout of the Rangers in an effort to save the bullpen. Murphy notched his first major league strikeout and was the only Rangers pitcher to record a scoreless inning that evening.
Cleveland Indians
On November 20, 2013, Murphy signed a 2-year, $12 million contract with the Cleveland Indians. The news was first broken by his youngest daughter, Faith. He was involved in the second known occurrence in MLB history of two balls in play simultaneously when he was confused by a ball accidentally thrown from the Cincinnati Reds' bullpen and tagged out before sliding back to third base in the seventh inning of a 9-2 Indians loss at Progressive Field on August 5, 2014.
On April 14, 2016, the Minnesota Twins signed Murphy to a minor league deal, but on the 25th, Murphy announced his retirement from baseball.
Broadcasting career
Since retiring from baseball, Murphy has worked as a broadcaster for Fox Sports Southwest. He has appeared as an analyst on Rangers LIVE pre and post game shows. He has also worked as a color commentator on Frisco RoughRiders broadcasts.