DIMBOA


DIMBOA is a naturally occurring hydroxamic acid, a benzoxazinoid. DIMBOA is a powerful antibiotic present in maize, wheat, and related grasses,
DIMBOA was first identified in maize in 1962 as the "corn sweet substance". Etiolated maize seedlings have a very sweet, almost saccharin-like taste due to their high DIMBOA content.
DIMBOA is stored as an inactive precursor, DIMBOA-glucoside, which is activated by glucosidases in response to insect feeding,
In maize, DIMBOA functions as natural defense against European corn borer larvae, beet armyworms, corn leaf aphids, other damaging insect pests, and pathogens, including fungi and bacteria. The exact level of DIMBOA varies between individual plants, but higher concentrations are typically found in young seedlings and the concentration decreases as the plant ages. Natural variation in the Bx1 gene influences the DIMBOA content of maize seedlings. In adult maize plants, the DIMBOA concentration is low, but it is induced rapidly in response to insect feeding.
In addition to serving as a direct defensive compound due to its toxicity, DIMBOA can also function as a signaling molecule, leading to the accumulation of callose in response to treatment with chitosan and aphid feeding.
DIMBOA can also form complexes with iron in the rhizosphere and thereby enhance maize iron supply.
Specialized insect pests such as the western corn rootworm can detect complexes between DIMBOA and iron and use these complexes for host identification and foraging.