Collateral circulation


Collateral circulation is the alternate circulation around a blocked artery or vein via another path, such as nearby minor vessels. It may occur via preexisting vascular redundancy, as in the circle of Willis in the brain, or it may occur via new branches formed between adjacent blood vessels, as in the eye after a retinal embolism. Its formation may be provoked by pathological conditions such as high vascular resistance or ischaemia.
An example of the usefulness of collateral circulation is a systemic thromboembolism in cats. This is when a thrombotic embolus lodges above the external iliac artery, blocking the external and internal iliac arteries and effectively shutting off all blood supply to the hind leg. Even though the main vessels to the leg are blocked, enough blood can get to the tissues in the leg via the collateral circulation to keep them alive.

Brain

in humans and some other animals is maintained via a network of collateral arteries that anastomose in the circle of Willis, which lies at the base of the brain. In the circle of Willis so-called communicating arteries exist between the front and back parts of the circle of Willis, as well as between the left and right side of the circle of Willis.

Heart

Another example in humans and some other animals is after an acute myocardial infarction. Collateral circulation in the heart tissue will sometimes bypass the blockage in the main artery and supply enough oxygenated blood to enable the cardiac tissue to survive and recover.

Eye

After central retinal vein occlusion, neovascularization may restore some blood flow to the retina, but the new vessels' bulk also presents a risk of causing acute glaucoma by blocking the drainage of aqueous humour. Collateral circulation is created around the blocked central vein via a generally winding path, usually from a branch vein to the choroid.

Truncal venous system

arising from congestion in the hepatic portal vein may give rise to collateral circulation between branches of the portal and caval veins of the liver, or between the two caval veins. Consequences of newly established venous collaterals arising from portal hypertension include esophageal varices and hemorrhoids.