Coarse facial features

• large, bulging head
• prominent scalp veins
• "saddle-like, flat bridged nose with broad, fleshy tip"
• large lips and tongue
• small, widely spaced and/or malformed teeth
• hypertrophic alveolar ridges and/or gums

Causes

• Acromegaly
• Alpha-mannosidosis type II
• Aspartylglycosaminuria
• Battaglia Neri syndrome
• Borjeson Syndrome
• Chromosome 6q deletion syndrome
• Coarse face - hypotonia - constipation
• Congenital hypothyroidism
• Dandy-Walker malformation
• Dyggve-Melchior-Clausen Syndrome
• Fucosidosis type 1
• Fucosidosis type II
• Gangliosidosis generalized GM1
• Gangliosidosis GM1
• GM1 gangliosidosis
• Goldberg syndrome
• Hyde-Forster-Mccarthy-Berry syndrome
• Hyper IgE
• Hypomelanosis of Ito
• I cell disease
• Immunodeficiency due to defect in MAPBP-interacting protein
• Infantile sialic acid storage disorder
• Job syndrome
• Mannosidosis
• McCune-Albright Syndrome
• Mental retardation
• Mental retardation
• Miescher's syndrome
• Morquio syndrome
• Morquio syndrome type A
• Morquio syndrome type B
• MPS 3 C
• MPS 3 D
• Mucolipidosis III
• Mucopolysaccharidosis type 2 Hunter syndrome- mild form
• Mucopolysaccharidosis type 2 Hunter syndrome- severe form
• Mucopolysaccharidosis type 3
• Mucopolysaccharidosis type 6
• Mucopolysaccharidosis type 7 Sly syndrome
• Mucopolysaccharidosis type I Hurler syndrome
• Mucopolysaccharidosis type I Hurler/Scheie syndrome
• Mucopolysaccharidosis type I Scheie syndrome
• Multiple endocrine abnormalities - adenylyl cyclase dysfunction
• Multiple endocrine neoplasia type 2b
• Neuraminidase deficiency
• Nodulosis-arthropathy-osteolysis syndrome
• Nonkeratan-sulfate-excreting Morquio syndrome
• Pituitary tumors
• Sialidosis type II
• Sialidosis type II
• Sialuria syndrome
• Simpson-Golabi-Behmel syndrome
• Simpson-Golabi-Behmel syndrome - type 1
• Skeletal dysplasia - coarse facies - mental retardation
• Spondyloepimetaphyseal dysplasia
• Sulfatidosis juvenile
• Winchester syndrome