His first mission came on 30 July 1942, when he and his radio operatorHarry Peulevé were parachuted in from a Halifax near Nîmes to set up and head the SCIENTIST network. However, they were dropped from too low an altitude and landed badly – de Baissac broke his ankle and Peulevé was so badly hurt he had to return to England. In the following months, de Baissac developed the SCIENTIST network in the Bordeaux region, receiving reinforcements in the form of Roger Landes and Mary Herbert. Certain resistance group concentrated their efforts for a joint attack on the submarine pens in the port and other operations in the Landes countryside. As explained by Paddy Ashdown in a BBC Timewatch documentary, due to "a Whitehall cock-up of major proportions", de Baissac was preparing to take explosives on board German ships in the harbour of Bordeaux when he heard explosions from the partly successful Operation Frankton. Had the Royal Marines of Operation Frankton cooperated with de Baissac, they could have jointly dealt a stronger blow, but SOE's policy of secrecy even from other parts of the British Forces prevented this. De Baissac worked closely with Francis Suttill and his Prosper-PHYSICIAN network in Paris, before briefly returning to London on the night of 17/18 March 1943 in a Lysander to announce that the network had 11,000 men at its disposal. In May 1943, Suttill warned de Baissac that he thought Henri Déricourt, a member of SCIENTIST, was working for the Germans just before de Baissac was parachuted back in at the full moon with new instructions. The parachute drops of men and supplied intensified, but on 23 June the Gestapo captured Suttill and hundreds of other agents and Resistance workers from Prosper-PHYSICIAN and other networks and attached groups. The SCIENTIST network was caught up in PHYSICIAN's fall and on the night of 16/17 August, Claude, Lise and Nicholas Bodington returned to England by Lysander, with Roger Landes replacing Claude at the head of SCIENTIST until November 1943. In February 1944 de Baissac was parachuted into Mayenne with an all-Mauritian team made up of his sister Lise, captain Jean-Marie Renaud-Danticolle and the radio operator Maurice Louis Larcher. His new mission was to amalgamate, arm and energise the Resistance groups in the region stretching from Caen to Laval. When D-Day came, he joined George Starr and his WHEELWRIGHT network in the south-west.