Chrysophanol
Chrysophanol, also known as chrysophanic acid, is a fungal isolate and a natural anthraquinone.Mechanism of action
Chrysophanol blocks the proliferation of colon cancer cells in vitro. It induces the necrosis of cells via a reduction in ATP levels. Chrysophanol attenuates the effects of lead exposure in mice by reducing hippocampal neuronal cytoplasmic edema, enhancing mitochondrial crista fusion, significantly increasing memory and learning abilities, reducing lead content in blood, heart, brain, spleen, kidney and liver, promoting superoxide dismutase and glutathione peroxidase activities and reducing malondialdehyde level in the brain, kidney and liver.
