CD98


CD98 is a glycoprotein that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter. LAT1 is a heterodimeric membrane transport protein that preferentially transports branched-chain and aromatic amino acids. LAT is highly expressed in brain capillaries relative to other tissues.
A functional LAT1 transporter is composed of two proteins encoded by two distinct genes: