CD244
CD244 is a human protein encoded by the gene. It is also known as Natural Killer Cell Receptor 2B4
This gene encodes a cell surface receptor expressed on natural killer cells mediating non-major histocompatibility complex restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CD244 can also be expressed on non-lymphocytes such as eosinophils, mast cells and dendritic cells.
