CARD10
Caspase recruitment domain-containing protein 10 is a protein in the CARD-CC protein family that in humans is encoded by the CARD10 gene.Function
The caspase recruitment domain is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. CARDs induce nuclear factor kappa-B activity through the IKK complex. CARD9, CARD10, CARD11, and CARD14 interact with BCL10 and are involved in NF-κB signaling complexes. Except for CARD9, these CARD proteins are members of the membrane-associated guanylate kinase family.Interactions
CARD10 has been shown to interact with BCL10.
