The Sovietbiosatellite program began in 1966 with Kosmos 110, and resumed in 1973 with Kosmos 605. Cooperation in space ventures between the Soviet Union and the United States was initiated in 1971, with the signing of the United States and Soviet Union in Science and Applications Agreement. The Soviet Union first offered to fly US experiments on a Kosmos biosatellite in 1974, only a few years after the termination of the U.S. biosatellite program. The offer was realized in 1975 when the first joint U.S./Soviet research were carried out on the Kosmos 782 mission. The Bion spacecraft were based on the Zenit and launches began in 1973 with primary emphasis on the problems of radiation effects on human beings. Launches in the program included Kosmos 110, 605, 690, 782, plus Nauka modules flown on Zenit-2Mreconnaissance satellites. 90 kg of equipment could be contained in the external Nauka module. The Soviet/Russian Bion program provided U.S. investigators a platform for launching Fundamental Space Biology and biomedical experiments into space. The Bion program, which began in 1966, included a series of missions that flew biological experiments using primates, rodents, insects, cells, and plants on a biosatellite in near-earth orbit. NASA became involved in the program in 1975 and participated in 9 of the 11 Bion missions. NASA ended its participation in the program with the Bion 11 mission launched in December 1996. The collaboration resulted in the flight of more than 100 U.S. experiments, one-half of all U.S. Life Sciences flight experiments accomplished with non-human subjects. The missions ranged from five days to around 22 days.
Bion-M
In 2005 the Bion program was resumed with three new satellites of the modified Bion-M type – the first flight was launched April 19, 2013 from Baikonur cosmodrome, Kazakhstan. The first satellite of the new series Bion-M1 featured an aquarium by the German Aerospace Center and carried 45 mice, 18 Mongolian gerbils, 15 geckos, snails, fish and micro-organisms into orbit for 30 days before re-entry and recovery. All the gerbils died due to a hardware failure, but condition of the rest of the experiments, including all geckos, was satisfactory. Half the mice died as was predicted. Bion-M2 is scheduled to launch in 2023 on a Soyuz 2.1a rocket to an altitude of 800 km. The orbiter will carry 75 mice and studies will focus on how they are affected at the molecular level by space radiation.