BRICHOS family


The BRICHOS family consists of a variety of proteins linked to major diseases, each containing a 100 amino acid BRICHOS domain that is thought to have a chaperone function.
These include BRI2, which is related to familial British and Danish dementia ; Chondromodulin-I, related to chondrosarcoma; CA11, related to stomach cancer; and surfactant protein C, related to respiratory distress syndrome.