Apoptosis-antagonizing transcription factor
Protein AATF is a protein that in humans is encoded by the AATF gene.Function
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.Interactions
Apoptosis-antagonizing transcription factor has been shown to interact with:
