Antibody Solutions Headquartered in Santa Clara , Calif., Antibody Solutions is a privately held American contract research organization that provides research and discovery services and fit-for-purpose antibodies to biopharmaceutical and diagnostic companies and academic researchers worldwide. The company’s services include monoclonal and polyclonal antibody and antigen development, molecular modeling, antibody sequencing and engineering, bioreactor technology, pharmacokinetic studies, antibody epitope binning , peptide synthesis, immunoassay development, ligand-binding assay analysis, and support for CAR-T research.History Antibody Solutions was founded in 1995 by current president, John Kenney, PhD, Judith Lynch-Kenney, and Dennis and Bette Gould. Dr. Kenney had managed the monoclonal antibody development laboratory for Syntex Research in Palo Alto, Calif., and Gould managed the MAb production facility for Syva Diagnostics. Gould left Antibody Solutions in 1997 and eventually became a vice president for Sepragen Corporation. Kenney and Gould were assisted in the startup of the company by Barry Bredt, who had the foresight to acquire the domain name , , for the company. Bredt later became director of the University of California at San Francisco’s General Clinical Research Center , and was a pioneer of the HIV/AIDS Diagnostics "EASYCD4." Bredt passed away on April 8, 2007. Antibody Solutions was incorporated in 1998 with Dr. Kenney as president and Judith Lynch-Kenney as chief financial officer . One of the first independent antibody discovery companies, the firm focused on custom antibody discovery for therapeutics, diagnostics and critical reagents . The company pioneered the use of bioreactors in antibody research by becoming the first CRO to produce antibodies in CELLine flasks in 2000. Antibody Solutions was headquartered for several years in Mountain View , a short distance from Shoreline Park , Moffett Field and the Googleplex . In 2011, the company moved to new facilities in Sunnyvale and then moved to its current location at 3033 Scott Blvd. in Santa Clara near the San Tomas Expressway in mid-2019.Partnerships Over the years, Antibody Solutions has had strategic agreements with a range of life science companies, including Open Monoclonal Technology, Inc., Reflexion Pharmaceuticals, Guava Technologies, Single-Cell Technologies, , Harbour Antibodies, OmniAb and Alloy Therapeutics.Research Independent research conducted by Antibody Solutions and published or presented at scientific conferences include the following: Generation of Neutralizing Human Monoclonal Antibodies Against a Therapeutic Target from the Alloy Therapeutics Mouse Generation Using a Molecular Modeling Platform to Guide Therapeutic Antibody Discovery Optimization of Therapeutic Discovery Strategies for Human Antibody Transgenic Animal Platforms Development of Antibody and PK, and ADA Assays for a Cystine Knot Fusion Protein A Rapid, High-Throughput Recombinant Antibody Expression System for Therapeutic Antibody Discovery and Validation Generation of Agonist and Antagonist Human Monoclonal Antibodies Against an Immune Checkpoint Target from the H2L2 Mouse Generation and Selection of Human Monoclonal Antibodies from the OmniRatTM Therapeutic Antibody Discovery at Antibody Solutions using the OmniAbTM Platform Development of human antibodies to human vascular endothelial growth factor -C and -D Obtaining Antibodies to Difficult Membrane Targets through DNA and Cell Immunization Next-Generation Therapeutic Antibody Discovery from Single B-cells Generation and Selection of Human Monoclonal Antibodies from the H2L2 Mouse Generation of Antibodies to Difficult Membrane Protein Targets Development of Antibodies and ELISAs to measure Free and Total Obiltoxaximab in the Presence of Anthrax Protective Antigen PA63 Discovery of Therapeutic Antibodies to Difficult Membrane ProteinsProducts and services Therapeutic antibody discovery Cell-receptor monoclonal antibody development In vivo animal study-grade antibodies development Molecular modeling Antibody sequencing Anti-idiotype antibody production Anti-protein antibodies for pharmacokinetics studies Immunogenicity assays for reagents and controls Immunoassay development Ligand-binding assay analysis Drug potency assay analysis Cell bank storage Full technical and project management
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