His current work deals with the role of cyclooxygenase-2 in cancer., He has previously been one of the three lead investigators of a major study on the role of aspirin in the prevention of breast cancer.
Withdrawal: p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression. Sachiyo Okayama, Levy Kopelovich, Gabriel Balmus, Robert S. Weiss, Brittney-Shea Herbert, Andrew J. Dannenberg, and Kotha Subbaramaiah J. Biol. Chem. 2020 295: 289. doi:10.1074/jbc.W119.012134 Withdrawal: Hsp90 and PKM2 drive the expression of aromatase in Li-Fraumeni syndrome breast adipose stromal cells. Kotha Subbaramaiah, Kristy A. Brown, Heba Zahid, Gabriel Balmus, Robert S. Weiss, Brittney-Shea Herbert, and Andrew J. Dannenberg J. Biol. Chem. 2020 295: 290. doi:10.1074/jbc.W119.012135 Withdrawal: Peroxisome proliferator-activated receptor γ ligands suppress the transcriptional activation of cyclooxygenase-2: Evidence for involvement of activator protein-1 and CREB-binding protein/p300. Kotha Subbaramaiah, Derrick T. Lin, Janice C. Hart, and Andrew J. Dannenberg J. Biol. Chem. 2020 295: 291. doi:10.1074/jbc.W119.012136 Withdrawal: Regulation of cyclooxygenase-2 mRNA stability by taxanes: Evidence for involvement of p38, MAPKAPK-2, and HuR. Kotha Subbaramaiah, Timothy P. Marmo, Dan A. Dixon, and Andrew J. Dannenberg J. Biol. Chem. 2020 295: 292. doi:10.1074/jbc.W119.012137 Withdrawal: Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease: Evidence for involvement of the transcription factor Egr-1. Kotha Subbaramaiah, Kazuhiko Yoshimatsu, Ellen Scherl, Kiron M. Das, Kenneth D. Glazier, Dragan Golijanin, Robert A. Soslow, Tadashi Tanabe, Hiroaki Naraba, and Andrew J. Dannenberg J. Biol. Chem. 2020 295: 293. doi:10.1074/jbc.W119.012138 Withdrawal: Histone deacetylase inhibitors suppress the induction of c-Jun and its target genes including COX-2. Kentaro Yamaguchi, Agnieszka Lantowski, Andrew J. Dannenberg, and Kotha Subbaramaiah J. Biol. Chem. 2020 295: 294. doi:10.1074/jbc.W119.012139 Withdrawal: EP2 and EP4 receptors regulate aromatase expression in human adipocytes and breast cancer cells: Evidence of a BRCA1 and p300 exchange. Kotha Subbaramaiah, Clifford Hudis, Sung-Hee Chang, Timothy Hla, and Andrew J. Dannenberg J. Biol. Chem. 2020 295: 295. doi:10.1074/jbc.W119.012140 Withdrawal: Cyclooxygenase-2-derived prostaglandin E2 stimulates Id-1 transcription. Kotha Subbaramaiah, Robert Benezra, Clifford Hudis, and Andrew J. Dannenberg J. Biol. Chem. 2020 295: 296. doi:10.1074/jbc.W119.012141 Withdrawal: HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling. Vikram D. Kekatpure, Andrew J. Dannenberg, and Kotha Subbaramaiah J. Biol. Chem. 2020 295: 297. doi:10.1074/jbc.W119.012142 Non-steroidal anti-inflammatory drugs and the risk of oral cancer: a nested case-control study. Sudbø J, Lee JJ, Lippman SM, Mork J, Sagen S, Flatner N, Ristimäki A, Sudbø A, Mao L, Zhou X, Kildal W, Evensen JF, Reith A, Dannenberg AJ. Lancet. 2005 Oct 15–21;366:1359-66. Retraction in: Horton R. Lancet. 2006 Feb 4;367:382.
Journals
According to Web of Science, he has published over 200 peer-reviewed articles, of which 27 have cited over 100 times. The most cited are:
"Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis" by Boolbol SK, Dannenberg AJ, Chadburn A, in Cancer Research 562556-2560 Times Cited: 401
"Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer" by Tucker ON, Dannenberg AJ, Yang FK, et al. in Cancer Research 59 987-990 Times Cited: 386
"Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck" by Chan G, Boyle JO, Yang EK, et al. in Cancer Research 59 991-994 Times Cited: 384
"COX‐2 is expressed in human pulmonary, colonic, and mammary tumors" RA Soslow, AJ Dannenberg, D Rush, BM Woerner, KN. in Cancer: 89 2637-2645 Times Cited: 289
Editor
COX-2: A New Target for Cancer Prevention and Treatment ed. by R. N. Dubois and A. J. Dannenberg Basel ; New York : Karger, 2003.
The role of COX-2 carcinogenesis by Andrew J Dannenberg; Raymond N Dubois; Steven M Dubinett; Nasser K Altorki; et al. Philadelphia, PA: Saunders, 2004. OCLC: 66570293
Peptic ulcer disease and other acid-related disorders by David Zakim; Andrew J Dannenberg Armonk, N.Y. : Academic Research Associates, 1991.
