Espiritu first worked as a DJ in a popular club, Euphoria and was discovered by guitarman Ramon "RJ" Jacinto in 1991. He made his television debut on That's Entertainment, a variety show hosted by the late German Moreno on GMA-7. He eventually started his professional career in December 1990 when he released his debut single "Humanap Ka Ng Panget". Andrew's career branched out as he began to star in comedy films based on his songs. In mid 1995, Espiritu founded an independent rap label named Dongalo Wreckords for the purpose of discovering and producing new rap talents, one of them being the rap groupSalbakuta, with their debut single "S2upid Luv" becoming a best-seller and spawning a film starring Espiritu. Espiritu spent some time in Japan in the late 1990s, performing in clubs and eventually releasing a CD single with two rap songs in Japanese about the misadventures of a tourist in Tokyo. In 2010, he was one of the judges in ABS-CBN's noontime variety/talent show Showtime. He later returned as a judge in the Showtime segment "Hype Best". He has notably collaborated with Sharon Cuneta, Willie Revillame, Joey de Leon, Regine Velasquez, Francis M., Ogie Alcasid, Janno Gibbs, Carlos Agassi, Death Threat, Salbakuta, DJs such as DJ Coki of Wil Time Big Time, DJ MOD of Showtime and DJ Belal of New York, and actresses such as Maricel Soriano, Ana Roces, Nanette Medved, Charlene Gonzalez, Vina Morales, Sheryl Cruz, Gelli de Belen, Alice Dixson, Amanda Page, Rufa Mae Quinto, Donita Rose and Rica Peralejo. Espiritu returned to acting in 2016 as Uge, the biological father of Serena in ABS-CBN's drama seriesDolce Amore. Andrews 1st Star Cinema movie was "Raketeros", a comedy movie was released in 2013 for the film companys 20th anniversary of Star Cinema and ABS-CBN Film Productions. Andrew returns to big screen via a newest wackiest comedy movie Sanggano, Sanggago’t Sanggwapo, marking his returning to Viva Films since his last movie was AB Normal College was released in 2004. Sanggano, Sanggago’t Sanggwapo was recently Premiered in theaters last September 2019, with co stars fellow comedians Astig Actor Dennis Padilla, former That's Entertainment Star and Mokong Actor Janno Gibbs, Louise Delos Reyes and special participation of the late Manoy Eddie Garcia and it will be directed by comedy director Al Tantay.
Controversies
Allegations of plagiarism
In 2018 Espiritu became involved in a plagiarism controversy when "Humanap Ka Ng Panget" was accused of being an unauthorized translation of the song "Find An Ugly Woman" by DJ Cash Money and MC Marvelous. A thread in the /r/Philippines subreddit called out the rapper for allegedly making a cover of "Find An Ugly Woman" without Cash Money Marvelous' permission, just after the noontime variety show ASAP aired a tribute performance to Espiritu.