Amidrine


Amidrine, Midrin, Nodolor, Duradrin, IDA, Migquin, Migrin-A, Migrazone or Epidrine is a combination drug consisting of paracetamol, dichloralphenazone and isometheptene used to treat migraines and severe, refractory headaches.

Components

Midrin was discontinued by Caraco Pharmaceuticals as of 2009, after an FDA seizure of 33 drugs manufactured by Caraco Pharmaceuticals due to cGMP violations. Generic forms of Amidrine were also discontinued due to loss of FDA grandfather approval status. Thus, manufacturer interest faded. The discontinued generic forms are: Amidrine, Duradrin, I.D.A, Migquin, Migrin-A and Migrazone. However, it is now being manufactured by Macoven Pharmaceuticals and marketed under the name Nodolor, as of April 2014. It can also be obtained through a compounding pharmacy with a doctor's prescription.