American Music Awards of 2010 38th Annual American Music Awards were held November 21 , 2010 , at the Nokia Theatre L.A. Live in Los Angeles , California . The awards recognized the most popular artists and albums from 2010's music list. Nominees were announced on October 12 , 2010 by Demi Lovato and Taio Cruz . Justin Bieber was nominated for, and won, four awards, including Artist of the Year . Usher and Eminem both won two awards; the former was nominated for three and the latter, five.Performers Presenters Heidi Klum Jenny McCarthy John Legend Eric Stonestreet Rico Rodriguez II Jessica Alba Agnez Mo Samuel L. Jackson Christina Milian Johnny Weir Taio Cruz Nicki Minaj Trey Songz Willow Smith Mandy Moore Sheryl Crow Natasha Bedingfield Kelly Osbourne Julianne Hough Keri Hilson Nathan Fillion Stana Katic Mike Posner Avril Lavigne The Band Perry Michael Chiklis Julie Benz Lady Antebellum Ryan Seacrest Christina Aguilera SealNominees and winners Ratings The ceremony was watched by 11.6 million viewers and received a 4.3 preliminary rating in the 18–49 demographic . This marked the lowest-ever ratings for the ceremony, with competition coming from NBC Sunday Night Football .
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