In about 1579 Alice married her first husband, Ferdinando Stanley, heir to the Earldom of Derby, and a claimant to the English throne. His mother, Lady Margaret Clifford, was heir presumptive to Queen Elizabeth I from 1578 until her death in 1596. On 25 September 1593, he succeeded as Earl of Derby and Lord of Mann; from that date onwards, Alice was styled as the Countess of Derby. Together Ferdinando and Alice had three daughters:
Her husband died on 16 April 1594, and when his mother died two years later, Alice's eldest daughter, Anne became heiress presumptive to Queen Elizabeth I. Upon the Queen's death in 1603, however, the crown passed to King James VI of Scotland who was descended from Margaret Tudor, the elder sister of King Henry VIII, whereas the Stanleys were descended from his younger sister, Mary Tudor, Queen of France. For a month after his death, his company of players performed at their home of Lathom House, Lancashire as The Countess of Derby's Men. They had been at Lathom House shortly before the Earl's death and had been known then as the Earl of Derby's Men. On 20 October 1600 she married her second husband Thomas Egerton, 1st Viscount Brackley, who on 21 July 1603 became Baron Ellesmere, and on 7 November 1616 Viscount Brackley. Less than two years after his own marriage to Alice, Thomas's son John married Alice's second eldest daughter Lady Frances. Together Alice and her new husband founded the Bridgewater Library. In 1601, Thomas Egerton bought Harefield Place in Middlesex, and in July 1602, the Queen was entertained at Harefield by the Egertons. Lady Alice had Haydon Hall in Eastcote built in 1630 after she became concerned that Lord Castlehaven would attempt to claim her estate in the event of her death. After she died in 1636, her eldest daughter reverted to her first married name, Lady Chandos, and became owner of the house. Alice was known as the Dowager Countess of Derby until her death.
Edmund Spenser
Alice was a noted patron of the arts, along with her sisters, Anne, Baroness Mounteagle and Elizabeth Spencer, Baroness Hunsdon. Poet Edmund Spenser was a distant relative of hers; in his pastoral poem, Colin Clouts Come Home Againe, he represented her as "Amaryllis", whereas her sisters, Anne and Elizabeth were "Charillis" and "Phyllis", and Alice's husband was "Amyntas". "Amaryllis" was described as "the highest in degree". Spenser also dedicated his The Teares of the Muses to her. Poet and author John Milton lived close to her Harefield Place residence.
Death
Alice died on 23 January 1637 and was buried on 28 January in St Mary the Virgin Church, Harefield. A monument dedicated to the memory of Alice and her three daughters was built at St Mary the Virgin, to her own specifications, before her death.
