Sir Alexander Ogston MD CM LLD was a British surgeon, famous for his discovery of Staphylococcus.
Life
Ogston was the eldest son of Amelia Cadenhead and her husband Prof. Francis Ogston, Professor of Medical Jurisprudence at the University of Aberdeen. He had a brother who was also a professor.
Ogston was reported to have called on Joseph Lister and rigorously followed his antiseptic principles. These are aptly phrased in a small ditty composed by his students. The spray, the spray, the antiseptic spray A.O. would shower it morning, night and day For every sort of scratch Where others would attach A sticking plaster patch He gave the spray. Ogston followed the work of other contemporaries such as Koch, J.C. Ewart from Edinburgh, and Kohler from Berne from the British Medical Association to continue his research. Following Kochs postulates and staining methods, Ogston set about isolating the causative organism of Davidson's wound. By experiment Ogston concluded that the optimal conditions for cultivation of this organism were hen's egg medium grown in small bottles shielded from contamination by glass 'shades. Using samples from 82 abscesses, Ogston successfully isolated bacteria from 65 samples, the others being referred to as "cold". He was then able to transfer pure colonies to guinea-pigs, white mice or wild mice. Ogston soon realised there were '"two forms of micrococcus: one in the form of chains or necklaces to which the name 'streptococcus' had been given and produced the more violent inflammation, and the other growing in masses or clusters , to which I gave the name 'staphylococcus' which cause a less violent inflammatory disease'. He also noted that a transferring a 1/146 016 000 dilution of the original pus sample could induce abscesses in new subjects. Ogston demonstrated that these bacteria could be killed by heat or carbolic acid, fulfilling Kochs postulates. He also noted that " micrococci so deleterious when injected" were seemingly "harmless on the surface of wounds and ulcers". An observation of the existence of some staphylococci as part of the normal flora. Ogston encountered a great deal of difficulty convincing the medical establishment of his observations on Staphylococcus. The Aberdeen branch of the BMA, received his findings with disbelief. The editor of the British Medical Journal stated at the time 'can anything good come out of Aberdeen'. After a careful study of the evidence presented by Ogston, his contemporary, Joseph Lister agreed with his findings however, another peer, Watson Cheyne was still sceptical. Given this local skeptisim, Ogston decided to present his discoveries to a surgical congress in Berlin where he had previously presented a paper "genu valgum" on 9 April 1880. Ogston delivered this presentation on absesses in German which was then published. He was subsequently made a 'Fellow' of the German Surgical Society despite his youth. The next year Ogston published his observations in the British Medical Journal. After this point his papers were refused and instead he published in the Journal of Anatomy and Physiology.
Military career
Ogston served in the 1884 Egyptian War and the Boer War. He was also instrumental in arguing for the creation of the Royal Army Medical Corps in 1898. During the First World War when over seventy years old, he was sent to assist with the management of severe trauma.
Private life
Ogston married twice. He had three children with his first wife Mary Jane Molly Ogston. They were Mary Letitia, Francis, Flora and Walter Henry. His wife died in 1873 and he later remarried and they had five children, Alfred James, Douglas John, Helen Charlotte Elizabeth, Constance Amelia Irene, Rose, Alexander and Ranald Frederick. Both Helen and Constance were active suffragettes.
The Surgical Society of the University of Aberdeen is named the "Ogston Society" in his honour. The University Department of Surgery also awards an annual prize in his honour to the best student in surgery.
