On July 14, 2009, the Pittsburgh Pirates signed Hanson as an international free agent for $90,000. In 2010, Hanson played his first year of rookie-levelMinor League Baseball as a member of the Gulf Coast League Pirates. In the 68 games he played in 2010, Hanson hit.324 with 28 runs batted in, 7 triples, and 20 stolen bases. In 2011, Hanson again played for the GCL Pirates. In 52 games, Hanson hit.263 with 35 RBIs, 7 triples, and 24 stolen bases. Hanson's 7 triples led the Gulf Coast League in 2011. In July 2012, Hanson was named the 40th-best prospect in baseball by Baseball America in their Midseason Top 50 Prospects List. Hanson spent the 2012 season with the Pirates' Class A affiliate, the West Virginia Power of the South Atlantic League. Hanson had a strong season for the Power. He played 124 games and hit.309 with 16 home runs, 62 runs batted in, 13 triples, 39 stolen bases, 55 walks, and 99 runs scored. He was named an All-Star. Prior to the 2013 season, Hanson was ranked as the 54th-best prospect in baseball by MLB.com, and the 61st-best prospect by Baseball America. Hanson began the 2013 season with the High-ABradenton Marauders. In 92 games with the Marauders, Hanson hit.281 with 7 home runs, 48 runs batted in, and 24 stolen bases. On July 28, Hanson was promoted to the Pirates' Double-A affiliate, the Altoona Curve. In 35 games with the Curve during the 2013 season, Hanson hit.255 with 10 RBIs, 6 stolen bases, and just a single home run. Hanson was added to the Pirates' 40-man roster on November 20, 2013. Hanson spent the entire 2014 season with the Curve. In 118 games, he hit.280 with 11 home runs, 64 runs batted in, 12 triples, and 25 stolen bases. In August 2014, the Pirates announced that they would be moving Hanson, primarily a shortstop, to second base. At the time of the announcement, Hanson had committed 61 errors in 227 games in 2013 and 2014. Larry Broadway, the Pirates' Director of Minor League Operations, indicated that the move was to increase Hanson's versatility, saying, "we still believe he can play shortstop and believe he will play shortstop for us at some point in the future. Adding this dimension to his game will give him additional opportunity to impact our organization at the Major League level when he is ready." Hanson spent the entire 2015 season with the Pirates' Triple-A affiliate, the Indianapolis Indians. Hanson played 117 games for the Indians and hit.263 with 6 home runs, 43 runs batted in, and 12 triples. Hanson also stole 35 bases, tying his personal best from 2012. Entering the 2016 season, MLB.com ranked Hanson as the 10th-best prospect in the Pirates organization, and the 6th-best prospect amongst second basemen. Hanson began the 2016 season with the Indianapolis Indians.
Pittsburgh Pirates
On May 16, 2016, the Pirates promoted Hanson to the major league club after Starling Marte went on paternity leave. Pirates manager Clint Hurdle said that Hanson would return to the minors when Marte returned. Hurdle noted that Hanson would likely be recalled again later in the season, but still had yet to prove himself in Triple-A. Hanson said that, when he called his mother to tell her the news, she accidentally hung up and celebrated, while Hanson waited in silence for nearly 10 minutes. On May 17, Hanson made his big league debut, striking out in a pinch-hit appearance. On May 18, Hanson recorded his first MLB hit. Entering the game in the 5th inning as a pinch hitter, Hanson reached base on an infield hit. Hanson said after the game that he planned to send the ball to his home in the Dominican Republic as a present for his mother. Hanson, out of minor league options, opened the 2017 season on the Pirates MLB roster. He was designated for assignment on June 2.
Chicago White Sox
On June 9, 2017 the Chicago White Sox claimed Hanson off waivers. Hanson was added to the team's 25-man roster the following day. On December 1, 2017, Hanson was non-tendered and became a free agent.
San Francisco Giants
Hanson signed a minor league contract with the San Francisco Giants on December 22, 2017, receiving a non-roster invitation to spring training. He began the 2018 season with the Sacramento River Cats of the Class AAA Pacific Coast League. After a hand injury to starting second baseman Joe Panik, Hanson was promoted by the Giants on April 28 after hitting.403 in 62 at bats for the River Cats with five doubles and three home runs. On March 28, 2019, Hanson was designated for assignment after failing to make the Opening Day roster.
Toronto Blue Jays
On April 2, 2019, the Giants traded Hanson, Derek Law, and Juan De Paula to the Toronto Blue Jays for Kevin Pillar. Hanson was called up by the Blue Jays on April 4. He was designated for assignment on May 3. He was outrighted to the Triple-A Buffalo Bisons on May 7. Hanson was released by the organization on August 3, 2019. He ended his stint with Toronto hitting only.163 in 18 games.
On January 23, 2020, Hanson signed a minor league deal with the Seattle Mariners with a perk of training with the Seattle mariners major league spring training camp. Hanson was released by the Mariners organization on June 25, 2020.
