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5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole
5,6-Dichloro-1-β--ribofuranosylbenzimidazole
is a
chemical compound
that inhibits
transcription
elongation
by
RNA Polymerase II
.
Sensitivity
to
DRB
is
dependent
on
DRB sensitivity inducing factor
,
negative elongation factor
, and
positive transcription elongation factor b
. DRB is a
nucleoside analog
and also inhibits some
protein kinases
.