In the first game of the season at FedExField in Landover, Maryland, Hokies quarterback Josh Jackson ran for a touchdown and threw another as the Hokies held off No. 22-ranked West Virginia 31–24. In the 52nd meeting between the two schools, a back-and-forth matchup was decided in the fourth quarter when Jackson rushed for a 46-yard gain to set up Travon McMillion's three-yard touchdown run with 6:30 left in the game. The Hokie defense, which gave up 592 total yards to the Mountaineers, came up big at the end, keeping West Virginia out of the endzone after two attempts from the 15-yard line as time expired. The win moved the Hokies to 1–0 on the season.
Delaware
The Hokies announced they would wear new "white Hokie stone" helmets for their first home game of the year against FCS Delaware. After allowing nearly 600 yards to West Virginia, Virginia Tech's defense rebounded nicely to record Bud Foster's 32nd shutout as the Hokies' defensive coordinator. The Blue Hens only got into Virginia Tech territory three times. Another Hokie hallmark, special teams, played an important role as Greg Stroman returned a punt for a touchdown late in the first quarter to give the Hokies a 7–0 lead. Quarterback Josh Jackson threw two scoring passes in the game as the Hokies were held to only 303 yards of total offense. However, it was enough as the Hokies moved to 2–0 on the season with a 27–0 win.
at East Carolina
Virginia Tech traveled to Greenville, North Carolina to take on East Carolina in a non-conference game. Things did not start well for the Hokies as the Pirates took an early 7–0 and then 17–7 lead as the first quarter ended. VT responded quickly thereafter, getting a touchdown catch from Cam Phillips and three Joey Slye field goals in the second quarter to take the lead at the half 23–17. In the second half the Hokies ran away with the game scoring five touchdowns in the third quarter to take a 57–17 lead. Four of the third quarter touchdowns were passes from quarterback Josh Jackson. Another touchdown in the fourth quarter gave the Hokies a 64–17 win over East Carolina. The Hokies rushed for 287 yards and Jackson passed for 388 yards and five touchdowns in the blowout. Phillips set a school record with 14 catches for 189 yards in the game. Meanwhile, the Hokie defense held the Pirates to only 281 total yards. The win moved the Hokies to 3–0 on the season.
Since the start of the 2016 season, two days prior to each game, Head Coach Justin Fuente has selected an outstanding special teams player to wear the #25 jersey in honor of former head coach, Frank Beamer, who wore #25 as a player for Virginia Tech. The players honored in the 2017 season are:
Game
Opponent
Player
Game 1
West Virginia
Anthony Shegog
Game 2
Delaware
Colton Taylor
Game 3
East Carolina
Greg Stroman
Game 4
Old Dominion
Deon Newsome
Game 5
Clemson
Terrell Edmunds
Game 6
Boston College
Greg Stroman
Game 7
North Carolina
Oscar Bradburn
Game 8
Duke
Ricky Walker
Game 9
Miami
Sean Huelskamp
Game 10
Georgia Tech
Tremaine Edmunds
Game 11
Pittsburgh
Andrew Motuapuaka
Game 12
Virginia
Jovonn Quillen
Camping World Bowl
Oklahoma State
Andrew Motuapuaka
2018 NFL Draft
The Hokies had five players selected in the 2018 NFL draft. The Edmunds brothers were both selected in the first round.
