2010 Western & Southern Financial Group Masters – Singles
was the defending champion and successfully defended his title, becoming the first player since Andre Agassi in 1996 to do so. He defeated Mardy Fish in the final 6–7, 7–6, 6–4. It was his fourth win at the event; he also won in 2005, 2007 and 2009. It was also Federer's 17th Masters tournament win putting him level with Agassi and his 63rd career title overall, equalling Björn Borg.Seeds
The top eight seeds receive a bye into the second round.Main draw
Finals
Section 2
Section 3
Section 4
