2006 Copa Sudamericana
The 2006 Copa Sudamericana de Clubes, officially the 2006 Copa Nissan Sudamericana de Clubes for sponsorship reasons, was an international football championship competition that was played by 34 teams in total, including 31 CONMEBOL teams and also three invited teams from CONCACAF.
Pachuca won their first title in history after defeating Colo-Colo tying 1–1 in the first leg in Mexico, and winning 2–1 in Chile that gave them the trophy. Pachuca only lost one game in the tournament, against Colombian Deportes Tolima 2–1 in their debut.
This was the second time a Mexican club reached the final, after UNAM lost the 2005 edition to Boca Juniors. Meanwhile, this was also the first time a Chilean club arrived to a final since the tournament's inauguration in 2002.
Also, this was the first time a Mexican representative won the Copa Sudamericana or any CONMEBOL tournament.
Qualified teams
The Copa Sudamericana 2006 tournament was the sixth edition of the Copa Sudamericana tournament.| Association | Team | Qualify method |
 Argentina7 Berths | Boca Juniors | Invitee and 2005 Copa Sudamericana Champions |
| Argentina 7 Berths | River Plate | Invitee |
| Argentina 7 Berths | Gimnasia y Esgrima | 2005–06 Argentine Primera División 2nd place overall |
| Argentina 7 Berths | Banfield | 2005–06 Argentine Primera División 4th place overall |
| Argentina 7 Berths | Velez Sarsfield | 2005–06 Argentine Primera División 5th place overall |
| Argentina 7 Berths | Lanús | 2005–06 Argentine Primera División 6th place |
| Argentina 7 Berths | San Lorenzo | 2005–06 Argentine Primera División 7th place |
 Bolivia2 Berths | Bolivar | Apertura 2005 Runners-Up |
| Bolivia 2 Berths | Universitario | Clausura 2005 3rd place |
 Brazil8 Berths | Corinthians | 2005 Série A winner |
| Brazil 8 Berths | Fluminense | 2005 Série A 5th place |
| Brazil 8 Berths | Atletico Paranaense | 2005 Série A 6th place |
| Brazil 8 Berths | Paraná | 2005 Série A 7th place |
| Brazil 8 Berths | Cruzeiro | 2005 Série A 8th place |
| Brazil 8 Berths | Botafogo | 2005 Série A 9th place |
| Brazil 8 Berths | Santos | 2005 Série A 10th place |
| Brazil 8 Berths | Vasco da Gama | 2005 Série A 12th place |
 Chile2 Berths | Colo-Colo | 2006 Fase Clasificatoria1st place |
| Chile 2 Berths | Huachipato | 2006 Fase Classificatoria 2nd place |
 Colombia2 Berths | Independiente Medellín | 2005 Reclasificacion 4th place |
| Colombia 2 Berths | Deportes Tolima | 2005 Reclasificacion 5th place |
 Costa Rica1 Berth | Alajuelense | Invitee |
 Ecuador2 Berths | LDU Quito | 2005 Apertura 1st place |
| Ecuador 2 Berths | El Nacional | 2005 Clausura 1st place |
 Mexico2 Berths | Toluca | Clausura 2006 1st place |
| Mexico 2 Berths | Pachuca | Clausura 2006 4th most eligible place |
 Paraguay2 Berths | Cerro Porteño | 2005 Liga Paraguaya 1st place overall |
| Paraguay 2 Berths | Libertad | 2005 Liga Paraguaya 4th place overall |
 Peru2 Berths | Universidad de San Martín | Campeonato Descentralizado 2005 4th place |
| Peru 2 Berths | Coronel Bolognesi | Campeonato Descentralizado 2005 5th place |
 Uruguay2 Berths | Nacional | 2005–06 Liguilla 3rd place |
| Uruguay 2 Berths | Central Espanol | 2005–06 Liguilla 4th place |
 Venezuela2 Berths | Carabobo | 2005–06 Primera División 4th place |
| Venezuela 2 Berths | Mineros | 2005–06 Primera División 5th place |
First stage
The table gives the teams in the first round gathered in elimination groups of 2 teams or 4 teams. Teams hosting the first game are on the left. Advancing teams are in bold.!colspan="5"|Chile/Peru Preliminary
!colspan="5"|Bolivia/Ecuador Preliminary
!colspan="5"|Paraguay/Uruguay Preliminary
!colspan="5"|Colombia/Venezuela Preliminary