1981 Copa Fraternidad
The 1981 Copa Fraternidad was the 11th edition of the Central American football club championship organized by UNCAF, the regional governing body of Central America.
Real C.D. España won their first title by winning the final round, as Club Deportivo Olimpia and C.D. Marathón quit the tournament.
Teams
Only El Salvador, Guatemala and Honduras sent representatives.| Association | Team | Qualifying method | Previous best | |
 El Salvador | Atlético Marte | 1980–81 Champions | 5th | 4th |
| El Salvador | Santiagueño | 1980–81 Runners-up | 3rd | First Round |
| El Salvador | Alianza | 1980–81 Third place | 7th | Runners-up |
| El Salvador | Águila | 1980–81 Fourth place | 6th | Runners-up |
 Guatemala | Xelajú | 1980 Champions | 1st | — |
| Guatemala | Juventud Retalteca | 1980 Runners-up | 1st | — |
| Guatemala | Comunicaciones | 1980 Third place | 9th | Champions |
| Guatemala | Suchitepéquez | 1980 Fourth place | 2nd | First Round |
 Honduras | Real España | 1980–81 Champions | 2nd | Runners-up |
| Honduras | Marathón | 1980–81 Runners-up | 2nd | First Round |
| Honduras | Olimpia | 1980–81 Third place | 2nd | Group stage |
| Honduras | Vida | 1980–81 Fourth place | 1st | — |
First Round
Second Round
Final Round
| 1981 Copa Fraternidad winners |
 Real España 1st title |