February 1 – Commissioner Bowie Kuhn announces the selection of Monte Irvin for the Hall of Fame by the Special Committee on the Negro Leagues.
February 27 – Chicago White Sox slugger Dick Allen signs a three-year contract for an estimated $250,000 per year, making him the highest-paid player in major league history.
March 5 – New York Yankees teammates Fritz Peterson and Mike Kekich arrive at Spring training and announce that wives and families have been swapped. Even the family dogs were traded.
March 20 – In a special election held by the Baseball Writers' Association of America, the late Roberto Clemente receives 393 of 424 votes to earn entry into the Hall of Fame. The Hall's Board of Directors had earlier waived the five-year-wait rule for Clemente.
March 29 – Orange baseballs, the brainchild of Oakland Athletics owner Charlie Finley, are used in the Athletics' 11–5 exhibition loss to the Cleveland Indians.
April–June
April 6:
*At Three Rivers Stadium, 51,695 fans watch as the jersey #21 of the late Roberto Clemente is retired. The Pittsburgh Pirates then beat the St. Louis Cardinals 7–5, with a ninth-inning rally.
*At Fenway Park, Ron Blomberg of the New York Yankees becomes the first designated hitter in major league history. He is walked by Boston Red Sox pitcher Luis Tiant in his first plate appearance.
April 17 – Philadelphia Phillies pitcher Dick Ruthven, signed from Fresno State, makes his major league debut without ever playing in the minor leagues. He starts against the Montreal Expos, allowing four runs in less than two innings, but did not figure in the decision as the Phillies won 9-6.
April 27 – In 50-degree weather, Kansas City Royals rookie Steve Busbyno-hits the host Detroit Tigers 3–0. It is the first Royals no-hitter, and the first in Tiger Stadium since Virgil Trucks' in. With the designated hitter rule in effect, Busby becomes the first pitcher of a no-hitter to not come to bat.
*In a 9–7 losing effort against the San Francisco Giants, St. Louis Cardinals ace Bob Gibson makes his 242nd consecutive start. It is a new 20th-century record, passing that of Red Ruffing who never pitched in relief the last ten years of his career.
May 9 – Johnny Bench of the Cincinnati Reds hit three home runs off Philadelphia's Steve Carlton for the second time in his career, in a 9–7 victory. Bench drove in seven runs.
May 24 – Willie Davis of the Los Angeles Dodgers gets 6 hits, all singles in a 7-3 19 inning loss to the New York Mets at Dodger Stadium. The record still stands as of 2017 for most hits in a game by a Dodgers player.
June 9 – After the Old Timers' Game at Shea Stadium, Willie Mays puts on his own show with a home run and a circus catch, and the New York Mets top the Los Angeles Dodgers 4–2. For Mays, older than a half dozen of the old Mets, it is the 655th homer of his career. Rusty Staub drives in two runs to back Jon Matlack. In the Old Timers' Game, the Brooklyn Dodgers/New York Yankees team loses to the Mets 1–0 in two innings.
June 13 – At Riverfront Stadium, St. Louis Cardinals pitcher Rick Wise loses a no-hitter when the Cincinnati Reds' Joe Morgan singles with one out in the ninth inning. It will be the only hit Wise allows in an 8–0 shutout win. Wise, who no-hit the Reds at Riverfront in, was bidding to join Addie Joss as the only pitchers to throw two no–hitters against the same team.
June 19
*In a Dodgers 4–0 victory over Cincinnati, Pete Rose and Willie Davis each collect their 2,000th career hit.
*Dave Winfield debuts in a San Diego Padre 7-3 loss to the Houston Astros. Winfield—who was also drafted by the Minnesota Vikings of the NFL and basketball's Atlanta Hawks and Utah Stars -- would go 1 for 4 in his debut, and never spend a day in the minor leagues. After a 22-year career, he is voted into baseball's Hall of Fame.
June 20
*Cy Acosta of the Chicago White Sox becomes the first American League pitcher to bat since the DH rule went into effect. Acosta strikes out in the eighth inning, but is credited with an 8–3 victory over the California Angels.
*Bobby Bonds leads off with a home run, but the Giants lose 7–5 to Cincinnati. It is Bonds' 22nd leadoff home run, breaking Lou Brock's National League record.
June 23 – Pitcher Ken Brett of the Philadelphia Phillies tops the Montreal Expos 7–2, and hits a home run for his fourth consecutive game, setting a major league record. Previously, Brett hit home runs on June 9, 13, and 18. He will total 10 for his career.
June 28 – Willie Stargell hits his 300th career home run helping the Pittsburgh Pirates beat the St. Louis Cardinals 6–0.
July
July 1 – Luis Aparicio of the Boston Red Sox steals the 500th base of his career in a 9–5 loss to the Milwaukee Brewers. It is the highest total in the American League since Eddie Collins retired in 1930.
July 3 – Brothers Gaylord Perry and Jim Perry pitch against each other for the only time in their careers. Neither finishes the game, but Gaylord is charged with the 5–4 loss. Two Norm Cash home runs help the Tigers.
July 4 – The Minnesota Twins bring their first-round June draft pick, pitcher Eddie Bane, straight to the major leagues, in an attempt to boost interest and attendance. Bane brings a 40-4 record with him from Arizona State University, and goes seven innings in his debut, a no-decision start. A crowd of 45,890 is on hand at Metropolitan Stadium.
July 9 – In a record-setting walkathon between the Cincinnati Reds and Montreal Expos, 25 bases on balls are handed out as Montreal strolls to an 11–6 win. Well off the American League's two-team mark of 30, this tops the National League record of 23, last reached on July 7, 1911. Six Montreal pitchers walk 16, one short of the record for an NL team, while two Reds pitchers walk nine. Hal King pinch hits a grand slam for the Reds in the 6th inning, his second pinch homer in nine days.
July 11:
*Jim Northrup, batting leadoff for the Detroit Tigers, drives in eight runs in a 14–2 win over Texas.
*In San Diego, the Pittsburgh Pirates drub the Padres 10–2. Willie Stargell contributes the 302nd home run of his career to pass Ralph Kiner as the all-time Pirate home run leader.
*Willie McCovey hits his 400th career home run helping San Francisco Giants beat Pittsburgh Pirates 12–0.
*Nolan Ryan pitches his second no hitter of the season (and second of seven for his career. He strikes out seventeen Detroit Tigers as the Angels win, 6–0.
July 20 – Wilbur Wood starts both games of a doubleheader for the Chicago White Sox, and loses both games to the New York Yankees, 12–2 & 7–0.
July 21 – Hank Aaron of the Atlanta Braves hits a Ken Brett fastball into the left-center field stands for a two-run home run during an 8–4 loss to the Philadelphia Phillies. It is career home run #700 for Aaron, only the second player to reach that milestone. Babe Ruth, with 714, is the other.
July 24 – The National League wins the All-Star Game at Kansas City, 7–1. A record 54 players are used, including Willie Mays, who strikes out in his final All-Star appearance, and Catfish Hunter, who sustains a fractured thumb that will sideline him for four weeks. Hunter has a 15–3 record at the time. Johnny Bench Bobby Bonds and Willie Davis All hit home runs for the N.L. And Bonds edged out Willie Davis for the game M.V.P. By 1 vote.
July 30 – At Oakland–Alameda County Coliseum, Jim Bibby of the Texas Rangers no-hits the Oakland Athletics 6–0. The no-hitter is the first in the history of the Washington Senators/Texas Rangers franchise.
August
August 1 – With the score tied at 2–2 in the top of the ninth at Fenway Park, in an incident that typifies both the Yankees – Red Sox rivalry and the feud between the two catchers involved, Thurman Munson of the New York Yankees barrels into Carlton Fisk of the Boston Red Sox while trying to score on Gene Michael's missed squeeze attempt. The incident triggers a 10-minute bench-clearing brawl in which both catchers are ejected. The Red Sox win 3–2 in the bottom of the ninth, with Mario Guerrero's two-out single scoring Bob Montgomery for the winning run.
August 5 – Atlanta Braves knuckleballer Phil Niekro no-hits the San Diego Padres 9–0. He walks three and strikes out four in recording the first no-hitter by the franchise in Atlanta.
August 6 – An exhibition game between the Milwaukee Brewers and the Atlanta Braves held at Milwaukee draws 33,337. The Brewers win, 7–5, in the fourth and last exhibition between the two teams. But the big thrill is provided by Hank Aaron, who hits a home run.
August 7 – Two days after Phil Niekro's no-hitter, the Braves purchase Joe Niekro, Phil's pitching brother, from the Detroit Tigers.
August 11 – Chicago White Sox rookie Brian Downing cracks his first major league hit, a home run off Detroit's Mickey Lolich. Downing's debut dinger is a first in the majors since at least 1945 – an inside-the-park homer. It'll be matched in two years by the Giants Johnnie LeMaster, who will do it in his first at bat.
August 15 – In Pittsburgh, Cincinnati Reds ace Jack Billingham beats the host Pittsburgh Pirates 1–0, notching his seventh shutout of the season. This ties the club record set by Hod Eller back in 1919.
August 17 – The New York Mets' Willie Mays hits the 660th home run of his career off Don Gullett of Cincinnati, but the Reds win 2–1 in 10 innings at Shea Stadium, after pinch hitter Hal King bats a walk-off home run, his third pinch homer of the year.
August 21 – Against the Cleveland Indians at Cleveland Stadium, Stan Bahnsen of the Chicago White Sox has a no-hitter broken up with two out in the ninth on a single by ex-teammate Walt Williams. The hit is the only one Bahnsen allows as the White Sox defeat the Indians 4-0.
September
September 3 – After 11 years at the helm, Ralph Houk resigns as the New York Yankees' manager. The 'Major' will manage the Detroit Tigers next season.
September 3 – The San Francisco Giants overcome a 7 – 1 deficit to beat the Los Angeles Dodgers 11 – 8 at Candlestick Park during a nationally televised Monday Night baseball game on NBC. Bobby Bonds hit a walk-off grand slam into the right field seats to win the game for the Giants.
September 6 – Brothers Felipe Alou and Matty Alou are released by the New York Yankees. Felipe is sold to the Montreal Expos and Matty goes to the St. Louis Cardinals.
September 7 – Whitey Herzog is fired by the Texas Rangers with the club in the American League West cellar at 47-91. Del Wilber serves as interim manager for one game before owner Bob Short names Billy Martin, fired by the Tigers earlier in the season, as Herzog's permanent replacement.
September 19 – The Pittsburgh Pirates lose the first game of a crucial three game series at Shea for first place 7–3 to the New York Mets when Cleon Jones has just the second two home run performance of his career.
September 20 – At Shea Stadium, in the top of the thirteenth inning, with Richie Zisk on first, the Pittsburgh Pirates' Dave Augustine belts what appears to be a home run over the left field wall. New York Mets left fielder Cleon Jones turns to play the ball off the wall and the ball hits the top of the wall and goes right into Jones' glove on the fly. He turns and throws to relay man Wayne Garrett, who throws home to catcherRon Hodges to nail Zisk at the plate. Following the "Ball on the Wall" play, the Mets win the game in the bottom half of the inning to move within half a game of the first place Pirates.
September 27 – Capping a memorable season, Nolan Ryan strikes out 16 Minnesota Twins en route to a 5–4, 11-inning win for the California Angels. Rich Reese is Ryan's final strikeout, his 383rd of the season, which breaks Sandy Koufax's season record.
September 30 – The New York Yankees play their final game in the original Yankee Stadium, losing to the Detroit Tigers 5–2. Yankee Stadium remains closed until 1976 while undergoing major renovations.
October–December
October 1 – Two make-up games were played after the scheduled end of the regular season on September 30: the Mets won at the Cubs 6–4 and the Pirates lost at home to the Padres 3–4; making a potential second game between the Cubs and Mets unnecessary.
October 8 – In Game 3 of the National League Championship Series, the New York Mets' Rusty Staub homers in the first and second innings as the Mets crush the Cincinnati Reds 9–2 at New York's Shea Stadium, in a game featuring a bench-clearing brawl involving future Phillies teammates Pete Rose and Bud Harrelson.
October 13 – The Oakland Athletics score two unearned runs in the third inning of game one of the 1973 World Series when the usually sure handed Félix Millán allows a ground ball to go through his legs. They are the only runs New York Mets starter Jon Matlack allows, but they are enough to give Oakland the 2–1 game one victory.
October 14 – In one of the more bizarre games in World Series history, the Mets defeat the Athletics 10-7 in 12 innings in Game 2 by scoring four runs in the 12th, three of which were the result of two errors by Oakland second baseman Mike Andrews. After the game, Athletics owner Charlie O. Finley forced Andrews to sign a false affidavit stating he was disabled, which would have rendered him ineligible for the remainder of the series. A's manager Dick Williams rallied to Andrews' defense and commissioner Bowie Kuhn nullified the affidavit. Nevertheless, Finley ordered Williams to bench Andrews for the remainder of the series. Williams, in defiance, sent Andrews to the plate as a pinch hitter in Game 4 in New York three nights later as the Mets' home crowd gave a standing ovation.
October 21 – Bert Campaneris and Reggie Jackson hit two-run home runs in the third inning as the Oakland Athletics defeated the New York Mets, 5–2, in Game Seven of the World Series, for their second straight World Championship. Jackson is selected the Series MVP.
October 23 – Athletics owner Charlie Finley reveals that he will not release manager Dick Williams from his contract unless he receives adequate compensation from the team that signs him. Williams had resigned following the World Series victory two days earlier.
January 9 – Lyn Lary, 66, shortstop for seven teams who led AL in steals in 1936
February 28 – Syl Simon, 75, infielder and pinch hitter for the Browns who played in the minor leagues after losing much of his left hand in an accident
March 12 – Frankie Frisch, 74, Hall of Fame second baseman for the Giants and Cardinals who scored 100 runs seven times, led the NL in steals three times, and was the 1931 MVP; a lifetime.316 hitter, he twice batted.400 in the World Series, and also managed the Cardinals to the 1934 World Series title
March 19 - Walt Leverenz, 84, Pitcher for the St. Louis Browns from 1913 to 1915
March 26 – George Sisler, 80, Hall of Fame first baseman for the St. Louis Browns widely recognized as the best defensive player ever at that position, he twice batted over.400 and hit.340 lifetime; the AL's 1922 MVP, he had a record 257 hits in 1920 and also led the league in steals four times
May 19 – Jim Moore, 69, pitcher who played from 1928 to 1932 for the Cleveland Indians and Chicago White Sox
May 21 – Herm Wehmeier, 46, pitcher who won 92 games in 13 seasons from 1945-58, primarily spent with the Cincinnati Reds
June 11 – Bill Burwell, 78, pitcher for the St. Louis Browns in 1920–21, later a scout
June 23 – Cliff Aberson, 51, two-sport athlete who was a left fielder for the Chicago Cubs from 1947 to 1949, and a halfback with Green Bay Packers in 1945
July 2 – Chick Hafey, 70, Hall of Fame left fielder for the St. Louis Cardinals and Cincinnati Reds, a career.316 hitter who made the first hit in All-Star history and was the first batting champion to wear eyeglasses
July 2 – George McBride, 92, shortstop for the Washington Senators known for his defense
July 7 – Paul Musser, 84, pitcher for the Washington Senators and Boston Red Sox
July 12 – Billy Urbanski, 70, shortstop for the Boston Braves from 1931 to 1936
August 7 – Wilbur Cooper, 81, pitcher who won over 200 games for the Pittsburgh Pirates, he was the first NL left-hander to reach that milestone
August 22 – George Cutshaw, 86, shortstop for the Dodgers, Pirates and Tigers who excelled on defense
September–December
September 5 – Jack Fournier, 83, first baseman for five teams who hit.313 lifetime, led NL in homers in 1924
September 10 – Roy Johnson, 70, outfielder who batted.300 four times and led AL in doubles and triples once each
September 11 – Del Baker, 81, member of the Detroit Tigers organization for 28 years as a catcher, coach and manager, he led the team to the 1940 pennant
September 14 – René Monteagudo, 57, Cuban pitcher and outfielder for the Senators and Phillies
October 8 – Ray Haley, 82, caught from 1915 through 1917 for the Boston Red Sox and Philadelphia Athletics
October 22 – Ben Van Dyke, 85, pitcher for the Philadelphia Phillies and Boston Red Sox
October 24 – Al Brazle, 60, pitcher who won 97 games for the St. Louis Cardinals, also leading the NL in saves twice
October 27 – Bennie Tate, 71, catcher for the Washington Senators, Chicago White Sox, Boston Red Sox and Chicago Cubs between 1924 and 1934
November 2 – Greasy Neale, 81, outfielder for the Cincinnati Reds who batted.357 in the 1919 World Series, but began coaching football to fill the time between baseball seasons
November 15 – Phil Todt, 72, fine defensive first baseman who played from 1924 to 1931 for the Boston Red Sox and Philadelphia Athletics
November 30 – Alex Metzler, 70, outfielder who hit.285 with a.374 OBP in 560 games for the Philadelphia Athletics, Chicago Cubs, Chicago White Sox, and St. Louis Browns from 1925 to 1930
December 10 – Joe Riggert, 86, outfielder for four seasons in the major leagues; holds the record for career minor league triples