14-Cinnamoyloxycodeinone


14-Cinnamoyloxycodeinone is the most potent example in a series of opiate analgesic drugs discovered in the 1960s, with > ×100 times the potency of morphine. It is a derivative of, being the 14-cinnamate ester. In another paper, Buckett assigns the potency as 177 with a range of ×101 - ×310. It may be of interest to researchers that the allyl group in this compound and in allylprodine overlay very closely.